AI is reshaping the very foundation of how businesses operate, demanding a new kind of leadership at the top. For C-level executives, keeping pace with this transformation means more than adapting—it requires a fundamental shift in how they think, lead, and make decisions. The stakes are high, and the speed of change is relentless. In this panel, we explore what it means to lead with intelligence—and how senior executives can develop the mindset, fluency, and capabilities needed to drive AI impact at scale. From understanding agentic systems and responsible AI governance to collaborating with technical teams and rethinking decision-making processes, this conversation unpacks the critical competencies required to lead in an AI-powered world.